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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SEC24C
All Species:
24.55
Human Site:
Y1046
Identified Species:
38.57
UniProt:
P53992
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P53992
NP_004913.2
1094
118325
Y1046
L
R
A
Q
R
S
R
Y
M
K
L
T
V
V
K
Chimpanzee
Pan troglodytes
XP_001145058
1094
118246
Y1046
L
R
A
Q
R
S
R
Y
M
K
L
T
V
V
K
Rhesus Macaque
Macaca mulatta
XP_001104565
998
107625
Q958
G
L
L
I
V
V
K
Q
E
D
K
L
E
M
L
Dog
Lupus familis
XP_850963
1096
118584
Y1048
L
R
A
Q
R
S
R
Y
M
K
L
I
V
V
K
Cat
Felis silvestris
Mouse
Mus musculus
Q3U2P1
1090
118764
F1046
L
R
E
Q
R
P
F
F
P
V
L
Y
V
I
R
Rat
Rattus norvegicus
NP_001102926
1095
118506
Y1047
L
R
A
Q
R
T
R
Y
M
K
L
I
V
V
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513100
1030
112379
Q990
M
K
L
T
V
V
K
Q
R
E
Q
P
E
M
V
Chicken
Gallus gallus
XP_421617
1147
124543
Y1099
L
H
L
Q
R
S
R
Y
M
K
L
I
I
V
K
Frog
Xenopus laevis
NP_001087832
1126
123503
Y1078
F
R
A
Q
R
P
R
Y
M
K
L
I
I
V
K
Zebra Danio
Brachydanio rerio
XP_700597
1315
142554
K1269
A
Q
R
S
R
Y
M
K
L
M
V
V
K
Q
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392952
1276
140829
C1227
V
R
M
E
R
H
R
C
M
R
L
T
I
V
R
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783728
1150
123558
Y1102
L
R
S
E
R
P
R
Y
M
K
L
T
L
V
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9M081
1080
116273
L1034
R
R
Q
R
C
S
Y
L
R
I
K
L
C
K
K
Baker's Yeast
Sacchar. cerevisiae
P53953
876
98925
N836
I
N
E
P
A
N
L
N
S
E
K
D
M
A
S
Red Bread Mold
Neurospora crassa
Q7S4P3
950
103512
V910
T
L
P
H
L
Y
I
V
R
E
D
G
E
P
S
Conservation
Percent
Protein Identity:
100
99.5
86.9
94.8
N.A.
26.9
92
N.A.
51.9
75.4
69
59.5
N.A.
N.A.
44.5
N.A.
52.6
Protein Similarity:
100
99.7
87.9
96.1
N.A.
45.8
94.4
N.A.
66.2
82.3
78.1
69
N.A.
N.A.
59.4
N.A.
64.3
P-Site Identity:
100
100
0
93.3
N.A.
40
86.6
N.A.
0
73.3
73.3
6.6
N.A.
N.A.
46.6
N.A.
66.6
P-Site Similarity:
100
100
13.3
93.3
N.A.
60
93.3
N.A.
33.3
80
80
33.3
N.A.
N.A.
80
N.A.
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
33
22.4
30
Protein Similarity:
N.A.
N.A.
N.A.
49.3
41.1
47
P-Site Identity:
N.A.
N.A.
N.A.
20
0
0
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
26.6
6.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
34
0
7
0
0
0
0
0
0
0
0
7
0
% A
% Cys:
0
0
0
0
7
0
0
7
0
0
0
0
7
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
7
7
7
0
0
0
% D
% Glu:
0
0
14
14
0
0
0
0
7
20
0
0
20
0
7
% E
% Phe:
7
0
0
0
0
0
7
7
0
0
0
0
0
0
0
% F
% Gly:
7
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% G
% His:
0
7
0
7
0
7
0
0
0
0
0
0
0
0
0
% H
% Ile:
7
0
0
7
0
0
7
0
0
7
0
27
20
7
0
% I
% Lys:
0
7
0
0
0
0
14
7
0
47
20
0
7
7
47
% K
% Leu:
47
14
20
0
7
0
7
7
7
0
60
14
7
0
7
% L
% Met:
7
0
7
0
0
0
7
0
54
7
0
0
7
14
0
% M
% Asn:
0
7
0
0
0
7
0
7
0
0
0
0
0
0
0
% N
% Pro:
0
0
7
7
0
20
0
0
7
0
0
7
0
7
0
% P
% Gln:
0
7
7
47
0
0
0
14
0
0
7
0
0
7
0
% Q
% Arg:
7
60
7
7
67
0
54
0
20
7
0
0
0
0
20
% R
% Ser:
0
0
7
7
0
34
0
0
7
0
0
0
0
0
14
% S
% Thr:
7
0
0
7
0
7
0
0
0
0
0
27
0
0
0
% T
% Val:
7
0
0
0
14
14
0
7
0
7
7
7
34
54
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
14
7
47
0
0
0
7
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _